Intrauterine Insemination (IUI)

A Strategic First Step — When Indicated

Intrauterine insemination (IUI) is a low to moderate intervention fertility treatment in which prepared sperm is placed directly into the uterus at the time of ovulation.

It is used selectively  not routinely  and only when the clinical profile supports it.

When IUI Makes Sense

IUI may be appropriate in cases of:

• Mild to moderate male factor infertility

• Unexplained infertility

• Cervical factor infertility

• Use of donor sperm when sperm retrieval is not feasible

It is typically combined with mild ovarian stimulation to improve timing and efficiency.

What to Expect

• Outpatient procedure

• No anesthesia

• Minimal discomfort

• Immediate return to daily activity

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Results & Limits

• Average success rates: up to 18–20% per cycle in optimal cases

• If pregnancy does not occur after 3–4 properly conducted cycles, continued IUI offers diminishing returns

At that point, IVF becomes the medically and strategically appropriate next step.

Bottom Line

IUI is not a shortcut to IVF  and it is not a long-term strategy.
Used correctly, it can be effective.
Used too long, it delays better outcomes.

References

• World Health Organization. Infertility Fact Sheet. Updated 2023.

• American Society for Reproductive Medicine. Evidence-Based Treatments for Unexplained Infertility. Fertility and Sterility, 2020.

• American College of Obstetricians and Gynecologists. Treating Infertility. FAQ179, 2021.

• European Society of Human Reproduction and Embryology. Guideline on Ovarian Stimulation for IUI. 2018 (current reference standard).

• Practice Committee of ASRM. Optimizing the use of intrauterine insemination. Fertility and Sterility, 2020

   

   

  No Medical Advice – Disclaimer of Liability
  Spyrakis Values does not provide medical advice, diagnosis, or treatment. Medical services are provided exclusively by legally licensed physicians/clinics. Clients are strongly advised to consult their personal physician before undergoing any medical treatment abroad. See Terms & Conditions.